Fetal alcohol spectrum disorders: Clinical phenotype among a high-risk group of children and adolescents in Korea.

摘要: Little is known about the prevalence and phenotype of fetal alcohol syndrome (FAS) or spectrum disorders (FASD) in Korea. This study was performed to describe distribution alcohol-related physical features a genetically homogeneous sample children adolescents institutional settings Children receiving services one seven institutions Seoul, Korea were screened for growth deficiency. Those who positive assessed using structured protocol key cardinal FAS, 11 additional dysmorphologic features. Based on these findings, categorized as Deferred (some characteristic FAS), No FAS. Groups compared specific number features, stratified by gender age. Of 307 screened, 87 received dysmorphology evaluation. Thirteen classified 44 Deferred, 30 The frequency 10 did not differ significantly FAS category. Palmar crease abnormalities more common (53.8%) than category (25.0%) (6.7%) (P = 0.003). A high across all groups found midfacial hypoplasia epicanthal folds, whereas only child exhibited ptosis. suggests that an FASD variant related ethnic differences range defects prenatal exposure may be present Korean population.