Hypoxia-inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer

作者: Peter Büchler , Howard A. Reber , Manuela Büchler , Shailesh Shrinkante , Markus W. Büchler

DOI: 10.1097/00006676-200301000-00010

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摘要: IntroductionThe microenvironment of low oxygen that is present in human pancreatic cancer vivo may actively influence tumor growth as well neovascularization.AimsTo determine whether hypoxia-inducible factor 1 (HIF-1) specifically activated by hypoxia vitro cells and

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