Effect of acth on cholesterol side-chain cleavage in rat adrenal mitochondria
作者： Alexander C. Brownie , Evan R. Simpson , Colin R. Jefcoate , George S. Boyd , William H. Orme-Johnson
DOI: 10.1016/S0006-291X(72)80164-5
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摘要: Summary The acute effect of ether stress on cholesterol side chain cleavage and cytochrome P-450 has been studied in intact rat adrenal mitochondria using light absorption EPR spectroscopy. is to increase the ratio high-spin low-spin oxidized this accompanied by an rate pregnenolone synthesis from mitochondrial cholesterol. Cycloheximide pre-treatment prevented these effects stress. action ACTH appears involve association with P-450.
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