Prevention and treatment of uterine bleeding in hematologic malignancy.

摘要: The purpose of this study was to provide a systematic review on prevention and treatment uterine bleeding in the setting hematologic malignancy. We performed MEDLINE, PubMed, EMBASE Cochrane searches with terms bleeding, hemorrhage, All identified literature sources were included review. is largely comprised case series pilot studies. No evidence-based protocols for gynecologists hematologists are available. majority centers menstrual suppression GnRH agonists malignancy, although no randomized trials could be identified. Review suggests that medical agonist therapy highly effective With respect acute can used successful patients, according Surgical should expeditiously if options fail control bleeding. Empiric algorithms discussed clinical settings proposed. More research necessary topic, goal develop guidelines gynecology hematology-oncology care providers. Close cooperation between specialties may improve morbidity mortality associated hematological malignancy future.