The Role of DLLs in Cancer: A Novel Therapeutic Target

作者: Meng-Xi Xiu , Yuan-Meng Liu , Bo-hai Kuang

DOI: 10.2147/OTT.S244860

关键词:

摘要: Delta-like ligands (DLLs) control Notch signaling. DLL1, DLL3 and DLL4 are frequently deregulated in cancer influence tumor growth, the vasculature immunity, which play different roles progression. DLLs have attracted intense research interest as anti-cancer therapeutics. In this review, we discuss role of summarize emerging DLL-relevant targeting methods to aid future studies.

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