Intravascular ultrasound imaging of saphenous vein grafts in vitro: Comparison with histologic and quantitative angiographic findings

摘要: Abstract The ubiquity of coronary artery disease and the resultant widespread use saphenous veins for bypass surgery has stimulated considerable interest in morphologic pathophysiologic alterations these vessels undergo after implantation. This study was undertaken to determine ability intravascular ultrasound identify characterize abnormalities vein grafts. Ten grafts excised at autopsy nine segments harvested during were examined with imaging, quantitative angiographic techniques histologic analysis. Intravascular lumen measurements strongly correlated arteriographic (r 0.91, SEE 0.5 mm). Wall thickness significantly greater long-term implantation than freshly (average 1.4 ± vs. 0.7 0.2 mm, p Thus, this preliminary demonstrates provide real-time cross-sectional images characterization their walls. modality may have important clinical applications, including detect serial changes graft intimal hyperplasia atherosclerosis.