Intra - operative Anesthesia Management in Patients Undergoing Surgical Irreversible Electroporation of the Pancreas, Liver, Kidney, and Retroperitoneal Tumors

摘要: Background: Irreversible electroporation (IRE) is a relatively new approach to the management of multiple types locally advanced soft tissue tumors. Unique peri-procedural anesthetic needed in safe and effective delivery this therapy. Objectives: This study analyzed IRE therapy relation for our initial cohort then established validated set best practical guidelines general anesthesia patients undergoing abdominal Patients Methods: An IRB-approved prospective data collection outcome protocol was utilized. broken up into two cohorts as follows: 38 (pts) which not defined or optimized 40-pt validation establish most efficacious protocols. Results: During delivery, deeper neuromuscular blockade required ensure that all retroperitoneal muscle excitation minimized. In 38-pt cohort, attempts treat hypertension (median SBP 190, range 185–215 median diastolic 98, 91–115) were made with various anti-hypertensives minimal-to-insufficient effects. The inhalation sevoflurane an approximate dose 8.0 volume percentage. Analgesic continuous remifentanil utilized epidural management, HTN tolerance Conclusions: Anesthetic deviates from standard medical regards depth analgesic during energy delivery. However, minor modifications allow efficient patient procedure.