Mortality and osteoporotic fractures: is the link causal, and is it modifiable?

摘要: Osteoporosis is a global problem with an expected increase in fracture prevalence and public health burden as the world's population ages. Although excess mortality well-described those low bone mineral density well recent hip vertebral fractures, some uncertainty remains about whether this link causal. Survival depends greatly on types, age, gender, race. Deaths are predominately due to comorbidities, but may also be attributed event itself, either directly or indirectly. The goal of osteoporosis care prevention fractures ultimately reduction morbidity mortality. Until recently, there have been no data showing that treatment improves mortality, even now extent these rather limited. Large observational cohort studies over considerable time needed determine improving quality will improve rates.