Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use

作者: Keith Coupland

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摘要: The present invention ralates to compounds of formula (I): wherein R is hydrogen (H) or c1-6 alkyl; and X defined such that - NH (X) COOH the residue an amino acid, which acid may itself optionally be substituted at any pendant group thereof by a carboxylic derivative thereof; salt thereof. use these compounds, in particular as potential anti-inflammatory immunomodulatory drugs, their preparation are described.

参考文章(4)
Keith Coupland, Nervonic acid compositions ,(1995)
Ching Yung. Ma, Alenka. Paquet, Robin C. McKellar, Effect of fatty N-acylamino acids on some functional properties of two food proteins Journal of Agricultural and Food Chemistry. ,vol. 41, pp. 1182- 1186 ,(1993) , 10.1021/JF00032A003
Keith Coupland, Yann Raoul, Nervonic acid derivatives, their preparation and use ,(2000)