The complexity of the translation ability of circRNAs.

作者: Javier T. Granados-Riveron , Guillermo Aquino-Jarquin

DOI: 10.1016/J.BBAGRM.2016.07.009

关键词:

摘要: Circular RNAs (circRNAs) are a new class of long non-coding RNAs that play a potential role in gene expression regulation, acting as efficient microRNAs sponges. The latest surprise concerning circRNAs is that we now know that they can serve as transcriptional activators in human cells, indicating that circRNAs are involved in important regulatory tasks. Recently, new insight has been gained about the coding potential of circular viroid RNAs, as well as the presence of Internal Ribosomal Entry Sites (IRES) allowing the formation of …

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