Linking Micronuclei to Chromosome Fragmentation.
作者： Emily M. Hatch , Martin W. Hetzer
DOI: 10.1016/J.CELL.2015.06.005
关键词:
摘要: Human cancer cells bear complex chromosome rearrangements that can be potential drivers of development. However, the molecular mechanisms underlying these have been unclear. Zhang et al. use a new technique combining live-cell imaging and single-cell sequencing to demonstrate chromosomes mis-segregated micronuclei frequently undergo chromothripsis-like in subsequent cell cycle.
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sci-hub.se 参考文章(10)
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