Nicotine induces a conditioned place preference in male Japanese quail (Coturnix japonica).

摘要: Abstract Visual stimuli may play an important role in the development and maintenance of addiction humans. Research with a visually-oriented animal model such as Japanese quail ( Coturnix japonica ) provide insight into how visual cues contribute to process. The aim current study was investigate rewarding properties nicotine male using biased conditioned place preference (CPP) procedure. Adult (N = 30) were allowed freely explore entire CPP apparatus during pre-test time spent each chamber measured. During conditioning sessions, administered (0.5, 1.0, or 2.0 mg/kg) saline then confined their initially least preferred chamber. On alternating days, all received Locomotor activity assessed both chambers. chambers had yellow green walls enhance salience context. Following 8 sessions (4 nicotine; 4 saline), post-test results indicated that treated 0.5 1.0 mg/kg significantly increased amount they nicotine-paired compared controls, suggesting produced CPP. Furthermore, 0.5 mg/kg showed significant increase locomotor repeated treatments. findings suggest have effect tentatively neuropharmacological mechanisms mediate for are conserved birds.