Chemical composition and larvicidal activity against Aedes mosquitoes of essential oils from Arisaema fargesii.

摘要: Background Dengue fever is caused by the spread of dengue virus Aedes mosquito vectors. Currently, most effective way to control preventing mosquitoes from spreading disease. Arisaema fargesii a Chinese herbal medicine commonly used repel mosquitoes. In our laboratory, anti-mosquito chemical components were extracted A. fargesii, and effects these substances on larvae examined. Results total, 48 compounds corresponding 98.79% total oil identified major linalool (12.38%), carvacrol (8.27%), eugenol (5.21%), β-selinene (5.36%). Essential had larvicidal activity against Ae. aegypti albopictus with LC50 values 40.49 mg/L, 47.01 respectively. The carvacrol, eugenol, 32.78, 56.34, 70.56, 136.03 mg/L larvae, 39.08, 52.07, 82.34, 151.74 respectively, larvae. Biochemical assays showed that activities acetylcholinesterase (AChE), monooxygenases (MO), glutathione-S-transferase (GST), p-Nitrophenyl acetate (p-NPA) esterase, α-esterase β-esterase significantly affected carvacrol. induced detoxification mechanism for action GST MO. Conclusion result indicates essential its isolated constituent have good inhibitory defense enzymes can be prevent fever. © 2019 Society Chemical Industry.