Metabolism and Pharmacokinetic Study of the Boron-Containing Prodrug of Belinostat (ZL277), a Pan HDAC Inhibitor with Enhanced Bioavailability.

作者: Changde Zhang , Shanchun Guo , Qiu Zhong , Qiang Zhang , Ahamed Hossain

DOI: 10.3390/PH12040180

关键词:

摘要: ZL277 is a prodrug of belinostat with enhanced bioavailability and efficacy as a pan histone deacetylase (HDAC) inhibitor. In this study, we investigated the metabolism and …

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