Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly
作者： Marcello Ceci , Cristina Gaviraghi , Chiara Gorrini , Leonardo A. Sala , Nina Offenhäuser
DOI: 10.1038/NATURE02160
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摘要: … Here we show that 60S subunits are activated by release of eIF6 (also termed p27 BBP ) 5,6 . In the cytoplasm, eIF6 is bound to free 60S but not to 80S. Furthermore, eIF6 interacts in …
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Udo Baron, Hermann Bujard, Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances. Methods in Enzymology. ,vol. 327, pp. 401- 421 ,(2000) , 10.1016/S0076-6879(00)27292-3
Tatyana V. Pestova, Ivan B. Lomakin, Joon H. Lee, Sang Ki Choi, Thomas E. Dever, Christopher U. T. Hellen, The joining of ribosomal subunits in eukaryotes requires eIF5B Nature. ,vol. 403, pp. 332- 335 ,(2000) , 10.1038/35002118
Mauricette Gaisne, Yann Chantrel, Claire Lions, Jacqueline Verdière, The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein. Genetics. ,vol. 148, pp. 559- 569 ,(1998)
Stephen K. Burley, Caroline M. Groft, Roland Beckmann, Andrej Sali, Crystal structures of ribosome anti-association factor IF6 Nature Structural & Molecular Biology. ,vol. 7, pp. 1156- 1164 ,(2000) , 10.1038/82017
Dorit Ron, Zhan Jiang, Lina Yao, Alicia Vagts, Ivan Diamond, Adrienne Gordon, Coordinated Movement of RACK1 with Activated βIIPKC Journal of Biological Chemistry. ,vol. 274, pp. 27039- 27046 ,(1999) , 10.1074/JBC.274.38.27039
Randall T. Peterson, Stuart L. Schreiber, Translation control: Connecting mitogens and the ribosome Current Biology. ,vol. 8, pp. R248- R250 ,(1998) , 10.1016/S0960-9822(98)70152-6
T. V. Pestova, V. G. Kolupaeva, I. B. Lomakin, E. V. Pilipenko, I. N. Shatsky, V. I. Agol, C. U. T. Hellen, Molecular mechanisms of translation initiation in eukaryotes. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 7029- 7036 ,(2001) , 10.1073/PNAS.111145798
Francesca Sanvito, Simonetta Piatti, Antonello Villa, Mario Bossi, Giovanna Lucchini, Pier Carlo Marchisio, Stefano Biffo, The beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly. Journal of Cell Biology. ,vol. 144, pp. 823- 837 ,(1999) , 10.1083/JCB.144.5.823
Bruno Senger, Denis L.J. Lafontaine, Jean-Sebastien Graindorge, Olivier Gadal, Alain Camasses, Ambaliou Sanni, Jean-Marie Garnier, Michael Breitenbach, Eduard Hurt, Franco Fasiolo, The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis. Molecular Cell. ,vol. 8, pp. 1363- 1373 ,(2001) , 10.1016/S1097-2765(01)00403-8
Daita Nadano, Goshi Ishihara, Chikage Aoki, Toko Yoshinaka, Shinji Irie, Taka-Aki Sato, Preparation and characterization of antibodies against human ribosomal proteins: heterogeneous expression of S11 and S30 in a panel of human cancer cell lines. Japanese Journal of Cancer Research. ,vol. 91, pp. 802- 810 ,(2000) , 10.1111/J.1349-7006.2000.TB01017.X