Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins

作者: Wei Leong Chew , Peter Paa , Swathi N. Manivannan , Liwei Chen , Priscilla D. Rajakumar

DOI: 10.1038/S41467-021-21559-9

关键词:

摘要: Many genetic diseases are caused by single-nucleotide polymorphisms. Base editors can correct these mutations at single-nucleotide resolution, but until recently, only allowed for …

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