Distribution of spontaneous chromosome breaks in human chromosomes.

作者: Pertti Aula , Harriet von Koskull

DOI: 10.1007/BF00291497

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摘要: Localization of chromosome breaks in human chromosomes was analyzed 264 peripheral lymphocyte cultures. Three hundred and sixty-nine could be exactly localized to a band or region the Paris Conference nomenclature. The distribution regions found nonrandom. Chromosome 3 alone had 23% 3p2 13% total breaks. Some other regions, such as 5p1, 9q1, 14q2, 16q2 also displayed clustering Sex less than expected. Spontaneous were almost exclusively located lightly stained G bands.

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