A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Steven G. Younkin, The role of Aβ42 in Alzheimer's disease Journal of Physiology-Paris. ,vol. 92, pp. 289- 292 ,(1998) , 10.1016/S0928-4257(98)80035-1

Patrick L. McGeer, Cyclo-oxygenase-2 inhibitors: rationale and therapeutic potential for Alzheimer's disease. Drugs & Aging. ,vol. 17, pp. 1- 11 ,(2000) , 10.2165/00002512-200017010-00001

Gerald K. McEvoy, AHFS Drug Information Oncology Issues. ,vol. 9, pp. 12- 13 ,(1994) , 10.1080/10463356.1994.11904493

Yue-Ming Li, Min Xu, Ming-Tain Lai, Qian Huang, José L. Castro, Jillian DiMuzio-Mower, Timothy Harrison, Colin Lellis, Alan Nadin, Joseph G. Neduvelil, R. Bruce Register, Mohinder K. Sardana, Mark S. Shearman, Adrian L. Smith, Xiao-Ping Shi, Kuo-Chang Yin, Jules A. Shafer, Stephen J. Gardell, Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1 Nature. ,vol. 405, pp. 689- 694 ,(2000) , 10.1038/35015085

Bart De Strooper, Wim Annaert, Philippe Cupers, Paul Saftig, Katleen Craessaerts, Jeffrey S. Mumm, Eric H. Schroeter, Vincent Schrijvers, Michael S. Wolfe, William J. Ray, Alison Goate, Raphael Kopan, A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature. ,vol. 398, pp. 518- 522 ,(1999) , 10.1038/19083

Brandon K Hadland, Nancy R Manley, Dong-ming Su, Gregory D Longmore, Chad L Moore, Michael S Wolfe, Eric H Schroeter, Raphael Kopan, γ-Secretase inhibitors repress thymocyte development Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 7487- 7491 ,(2001) , 10.1073/PNAS.131202798

Han Li, Alanna K. Rahm, Dennis J. Ahnen, Alan L. Stoumen, Tyler S. Finn, Benjamin H. Fryer, Gary A. Piazza, Rifat Pamukcu, Apoptosis Primarily Accounts for the Growth-inhibitory Properties of Sulindac Metabolites and Involves a Mechanism That Is Independent of Cyclooxygenase Inhibition, Cell Cycle Arrest, and p53 Induction Cancer Research. ,vol. 57, pp. 2452- 2459 ,(1997)

Mary Lou Oster-Granite, Donna L. McPhie, Jane Greenan, Rachael L. Neve, Age-Dependent Neuronal and Synaptic Degeneration in Mice Transgenic for the C Terminus of the Amyloid Precursor Protein The Journal of Neuroscience. ,vol. 16, pp. 6732- 6741 ,(1996) , 10.1523/JNEUROSCI.16-21-06732.1996

Takeshi Kawarabayashi, Linda H. Younkin, Takaomi C. Saido, Mikio Shoji, Karen Hsiao Ashe, Steven G. Younkin, Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease The Journal of Neuroscience. ,vol. 21, pp. 372- 381 ,(2001) , 10.1523/JNEUROSCI.21-02-00372.2001

David E. Kang, Claus U. Pietrzik, Larry Baum, Nathalie Chevallier, David E. Merriam, Maria Z. Kounnas, Steven L. Wagner, Juan C. Troncoso, Claudia H. Kawas, Robert Katzman, Edward H. Koo, Modulation of amyloid β-protein clearance and Alzheimer’s disease susceptibility by the LDL receptor–related protein pathway Journal of Clinical Investigation. ,vol. 106, pp. 1159- 1166 ,(2000) , 10.1172/JCI11013