S(blue) cone pathway vulnerability in retinitis pigmentosa, diabetes and glaucoma
作者： V C Greenstein , D C Hood , R E Carr , D Steinberger , R Ritch
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摘要: A variety of retinal disease lead to a decrease in the sensitivity S (blue) cone pathways. To determine possible sites and mechanisms this loss we compared sensitivities an (blue/pi-1) M (green/pi-4) pathway patients with diseases that differ as their primary locus loss. The were assessed retinitis pigmentosa, insulin-dependent diabetes mellitus open-angle glaucoma using Stiles two-color increment threshold technique. greater than was found for all three groups; however, diabetic showed more selective results suggest multiple are involved combined effects metabolic abnormalities hypoxia contribute
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