LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization.

作者: Akiko Kuma , Makoto Matsui , Noboru Mizushima

DOI: 10.4161/AUTO.4012

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摘要: … We next determined whether GFP-LC3 can be incorporated into protein aggregates composed of unrelated proteins. We utilized expanded polyglutamine (polyQ) to generate …

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