DNA Microarrays Technology: Overview and Current Status

作者: Alex Sánchez-Pla

DOI: 10.1016/B978-0-444-62651-6.00001-5

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摘要: Abstract DNA microarray is a recent technology in which high number of nucleic acid sequences are bound to surface and used identify quantify the on sample by letting both groups sequences, array, hybridize, subsequently identifying hybridized sequences. Microarrays have been applied all types biological medical problems, from cancer prognosis study circadian cycles fruit ripening. The most common applications gene expression but they also heavily genetic variation, detect aberrant numbers copies associated with diseases, many other situations. technique choice during first decade twenty-first century for applications, advent next-generation sequencing techniques it may be expected that some their adopted this new technology, especially those where microarrays show limitations.

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