A neuropsychological perspective on the role of the prefrontal cortex in reward processing and decision-making

摘要: Publisher Summary The aim of this chapter is to highlight insights from the field neuropsychology into prefrontal brain functions such as reward processing and decision-making. ventromedial cortex (VMPC) in humans plays important roles cognition emotion regulation. Lesions human have been shown impair higher-order behavioral guidance, social conduct, emotional regulation, even though language, movement, perception are spared. When VMPC damaged, patients fail appreciate take account long-term consequences their decisions. also lead an increase utilitarian moral judgments irrational responses unfair interactions, both which attributed dysregulation. Aging has cause similar decision-making deficits a substantial subset older adults, suggesting that region can be disproportionately affected by neurological aging.