Inhaled therapeutics for prevention and treatment of pneumonia

作者: Amar Safdar , Samuel A Shelburne , Scott E Evans , Burton F Dickey

DOI: 10.1517/14740330903036083

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摘要: The lungs are the most common site of serious infection owing to their large surface area exposed external environment and minimum barrier defense. However, this architecture makes readily available for topical therapy. Therapeutic aerosols include those directed towards improving mucociliary clearance pathogens, stimulation innate resistance microbial infection, cytokine immune function delivery antibiotics. In our opinion inhaled antimicrobials underused, especially in patients with difficult-to-treat lung infections. use antimicrobial therapy has become an important part treatment airway Pseudomonas aeruginosa cystic fibrosis prevention invasive fungal undergoing heart transplantation. Cytokine also been explored neoplastic infectious disease. choice pulmonary drug systems remains critical as air-jet ultr...

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