Reactivity of the secondary benzylic Grignard reagent from 1-phenylethyl chloride with aldehydes and ketones. More evidence for the rearrangement mechanism in benzyl Grignard reactions
作者： Claude Bernardon
DOI: 10.1016/0022-328X(89)87200-6
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摘要: Abstract Additional evidence for the mechanism proposed previously to account diol formation in reaction of Grignard reagent from benzyl chloride with aldehydes has been obtained a study interaction 1-phenylethyl carbonyl compounds. This reacts ketones (except non-enolisable ketones) give normal alcohols low yields, and diols. However, contrast that formed benzylmagnesium chloride, an unstable trienic alcohol rearrangement corresponding alkoxide could be isolated some case as major product, providing confirmatory existence initial reversible benzylic reagents
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