Bioanalytical Studies Based on Lectin–Carbohydrate Interactions Measured by Ellipsometry and Surface Plasmon Resonance Techniques

摘要: Publisher Summary A biosensor is an analytical device, which exploits a biological detection or recognition system for target molecule macromolecule, in conjunction with physiological transducer, converts the event into usable output signal. The sensor comprises three essential components: detector, recognizes physical stimulus; stimulus to useful, invariably electronic output; and itself, involves amplification display appropriate format. Biosensors may be divided six basic groups, depending on transduction process: electrochemical (potentiometry, amperometry, voltammetry), electrical (surface conductivity, capacitance), thermal (calorimetry, enzyme thermistor), magnetic (paramagnetism), piezoelectric (thickness-shear mode, surface acoustic waves, plate Love wave) optical (fluorescence, luminescence, reflection, scattering, plasmon resonance (SPR)). SPR powerful biosensing technique non-label bioaffinity interaction analysis (antigen—antibody, lectin—saccharide receptor—hormone). can employed as of interactions.