Nitric oxide scavenging rates of solubilized resveratrol and flavonoids.
作者： Yoshimi Sueishi , Masashi Hori
DOI: 10.1016/J.NIOX.2012.12.002
关键词:
摘要: Abstract Relative nitric oxide scavenging rates of water-insoluble lipophilic antioxidants, such as resveratrol and flavonoids were determined using a β-cyclodextrin analog, DM-β-CD (heptakis(2,6-di-O-methyl)-β-cyclodextrin) solubilizer. Antioxidant-mediated decrease NO concentration was measured with the electron spin resonance-based PTIO (2-phenyl-4,4,5,5-methylimidazoline-1-oxyl 3-oxide) method, from which calculated. Because both antioxidant form inclusion complex DM-β-CD, kinetic treatment necessary to calculate rates. Resveratrol showed highest rate among tested antioxidants. The magnitudes in order of: resveratrol > catechin ≈ myricetin > epicatechin > epigallocatechin gallate > kaempferol. This is not agreement oxygen radical rates: i.e., myricetin > epigallocatechin gallate > catechin ≈ epicatechin > resveratrol > kaempferol. antioxidants lower than hydrophilic uric acid caffeic acids. Previous redox potential measurement revealed that occurs through non-free mechanism, indicating capacity dependent on nature reaction.
elsevier.com
sci-hub.se 参考文章(21)
Garry R. Buettner, Ronald P. Mason, [9] Spin-trapping methods for detecting superoxide and hydroxyl free radicals in vitro and in vivo Methods in Enzymology. ,vol. 186, pp. 127- 133 ,(1990) , 10.1016/0076-6879(90)86101-Z
Takaaki Akaike, Masaki Yoshida, Yoichi Miyamoto, Keizo Sato, Masahiro Kohno, Kazumi Sasamoto, Kiminori Miyazaki, Shoichi Ueda, Hiroshi Maeda, Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction. Biochemistry. ,vol. 32, pp. 827- 832 ,(1993) , 10.1021/BI00054A013
Dudley W. Lamming, Jason G. Wood, David A. Sinclair, Small molecules that regulate lifespan: evidence for xenohormesis. Molecular Microbiology. ,vol. 53, pp. 1003- 1009 ,(2004) , 10.1111/J.1365-2958.2004.04209.X
Dharmendra V. Bangalore, William McGlynn, Darren D. Scott, Effect of beta-cyclodextrin in improving the correlation between lycopene concentration and ORAC values. Journal of Agricultural and Food Chemistry. ,vol. 53, pp. 1878- 1883 ,(2005) , 10.1021/JF048258M
Vittorio Bertacche, Natascia Lorenzi, Donatella Nava, Elena Pini, Chiara Sinico, HOST-GUEST INTERACTION STUDY OF RESVERATROL WITH NATURAL AND MODIFIED CYCLODEXTRINS Journal of Inclusion Phenomena and Macrocyclic Chemistry. ,vol. 55, pp. 279- 287 ,(2006) , 10.1007/S10847-006-9047-8
Dejian Huang, Boxin Ou, Ronald L. Prior, The Chemistry behind Antioxidant Capacity Assays Journal of Agricultural and Food Chemistry. ,vol. 53, pp. 1841- 1856 ,(2005) , 10.1021/JF030723C
Takashi Ishizu, Kanako Kintsu, Hideji Yamamoto, NMR Study of the Solution Structures of the Inclusion Complexes of β-Cyclodextrin with (+)-Catechin and (−)-Epicatechin Journal of Physical Chemistry B. ,vol. 103, pp. 8992- 8997 ,(1999) , 10.1021/JP991178E
Yoshimi Sueishi, Misa Ishikawa, Daisuke Yoshioka, Nobuyuki Endoh, Shigeru Oowada, Masashi Shimmei, Hirotada Fujii, Yashige Kotake, Oxygen radical absorbance capacity (ORAC) of cyclodextrin-solubilized flavonoids, resveratrol and astaxanthin as measured with the ORAC-EPR method Journal of Clinical Biochemistry and Nutrition. ,vol. 50, pp. 127- 132 ,(2012) , 10.3164/JCBN.11-21
Takashi Ishizu, Shinya Kajitani, Hiroyuki Tsutsumi, Hideji Yamamoto, Kazunobu Harano, Diastereomeric difference of inclusion modes between (−)‐epicatechin gallate, (−)‐epigallocatechin gallate and (+)‐gallocatechin gallate, with β‐cyclodextrin in aqueous solvent Magnetic Resonance in Chemistry. ,vol. 46, pp. 448- 456 ,(2008) , 10.1002/MRC.2198
Yoshimi Sueishi, Masashi Hori, Masakazu Kita, Yashige Kotake, Nitric oxide (NO) scavenging capacity of natural antioxidants. Food Chemistry. ,vol. 129, pp. 866- 870 ,(2011) , 10.1016/J.FOODCHEM.2011.05.036