Strongly Directing Substituents in the Radical Arylation of Substituted Benzenes

摘要: Although general interest in radical arylation reactions has grown rapidly recent years, poor regioselectivities and the need to use a large excess of radical-accepting arene have hindered their application substituted benzenes. We now describe experimental computational investigations into substituent effects that lead regioselective addition based on discovery anilines as outstanding substrates for arylations.