No evidence for decreased incidence of aspiration after rapid sequence induction

摘要: The purpose of this structured, evidence-based, clinical update was to determine if rapid sequence induction is a safe or effective technique decrease the risk aspiration other complications airway management. In June 2006 structured search medline from 1966 present using OVID software undertaken with assistance reference librarian. Medical subject headings and text words describing intubation (RSI), crash intubation, cricoid pressure emergency were employed. OVID’s therapy (sensitivity) algorithm used maximize detection randomized trials while excluding non-randomized research. bibliographies eligible publications hand-searched identify not identified in electronic search. A total 184 which 163 controlled (RCTs). Of these trials, 126 evaluated different drug regimens 114 being RCTs. Only 21 non-pharmacologic aspects RSI 18 RCTs identified. parallel found 52 evaluating (outside context an technique) 44 classified as Definitive outcomes such prevention mortality benefit could be trials. Likewise, impact on adverse components ascertained. An absence evidence suggests that decision use during management can neither supported nor discouraged basis quality evidence.