Some new psychoactive substances: precursor chemicals and synthesis-driven end-products.

作者: Michael Collins

DOI: 10.1002/DTA.315

关键词:

摘要: This paper describes some of the new classes 'designer drugs' being encountered today by forensic scientists and law enforcement agencies in Europe, United States, Australia. In particular, it concentrates on cathinone derivatives, tryptamines, new-generation phenethylamines, synthetic cannabinoids. The approaches towards many these designer drugs including a discussion chemical precursors used syntheses are presented. Many today's so-called exist as result legitimate research into medical conditions natural product chemistry. A link between published open scientific literature exploitation this clandestine manufacture for illicit purposes is drawn.

参考文章(49)
Konstantin Yu Zhingel, William Dovensky, Arthur Crossman, Andrew Allen, Ephedrone: 2-Methylamino-1-Phenylpropan-1-One (Jeff) Journal of Forensic Sciences. ,vol. 36, pp. 915- 920 ,(1991) , 10.1520/JFS13103J
Ernst Sp�th, Über dieAnhalonium-Alkaloide Monatshefte Fur Chemie. ,vol. 40, pp. 129- 154 ,(1919) , 10.1007/BF01524590
Joseph B. Blair, Deborah Kurrasch-Orbaugh, Danuta Marona-Lewicka, Medhane G. Cumbay, Val J. Watts, Eric L. Barker, David E. Nichols, Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines. Journal of Medicinal Chemistry. ,vol. 43, pp. 4701- 4710 ,(2000) , 10.1021/JM000339W
Kevin F. Foley, Nicholas V. Cozzi, Novel aminopropiophenones as potential antidepressants Drug Development Research. ,vol. 60, pp. 252- 260 ,(2003) , 10.1002/DDR.10297
St. Szára, Dimethyltryptamin: Its metabolism in man; the relation of its psychotic effect to the serotonin metabolism Cellular and Molecular Life Sciences. ,vol. 12, pp. 441- 442 ,(1956) , 10.1007/BF02157378
Richard H. F. Manske, a Synthesis of the Methyltryptamines and Some Derivatives Canadian journal of research. ,vol. 5, pp. 592- 600 ,(1931) , 10.1139/CJR31-097
Uroš Laban, Deborah Kurrasch-Orbaugh, Danuta Marona-Lewicka, David E. Nichols, A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties Bioorganic & Medicinal Chemistry Letters. ,vol. 11, pp. 793- 795 ,(2001) , 10.1016/S0960-894X(01)00062-2
Frank Sporkert, Fritz Pragst, Rainer Bachus, Florian Masuhr, Lutz Harms, Determination of cathinone, cathine and norephedrine in hair of Yemenite khat chewers Forensic Science International. ,vol. 133, pp. 39- 46 ,(2003) , 10.1016/S0379-0738(03)00048-3