Epidemiosurveillance of antimicrobial compound resistance of Staphylococcus intermedius clinical isolates from canine pyodermas

作者: J.L. Pellerin , P. Bourdeau , H. Sebbag , J.M. Person

DOI: 10.1016/S0147-9571(97)00026-X

关键词:

摘要: In a retrospective study, 131 Staphylococcus intermedius strains isolated from apparently healthy dogs, and 187 dog pyodermas in the clinical microbiology laboratory at National Veterinary School Nantes, during three successive periods: 1986-87, 1992-93 1995-96, were investigated compared for their antimicrobial susceptibility. Results indicated that 60% to 65% of susceptible Chloramphenicol Doxycyclin, 80% macrolides (Erythromycin, Lincomycin Clindamycin) Trimethoprim/Sulfonamide association. More than 95% betalactamins tested: Oxacillin, Amoxycillin/Clavulanic acid, Cephalexin, Gentamicin, Fucidic Acid two quinolones: Enrofloxacin Marbofloxacin. This last group is made up choice antibacterials treatment pyoderma. Many different resistance patterns observed each period with no really predominant profile, because low plasmidic vs chromosomal balance genetic basis antibacterial intermedius. However, proportion multiresistant (> or = 3 drugs) increased 10.8% first period, 28% third period. frequency suggests strongly that, as aureus human infections, prescription antibiotic compounds increases prevalence resistant strains.

参考文章(29)
Ihrke Pj, Horwitz Ln, McGinley K, Marples Rr, Schwartzman Rm, Microbiology of normal and seborrheic canine skin. American Journal of Veterinary Research. ,vol. 39, pp. 1487- 1489 ,(1978)
Miller Wh, Long Re, Medleau L, Brown J, Frequency and antimicrobial susceptibility of Staphylococcus species isolated from canine pyodermas. American Journal of Veterinary Research. ,vol. 47, pp. 229- 231 ,(1986)
G D Overturf, D A Talan, K Singer, N Anderson, J I Miller, R T Greene, S Froman, Phage typing of Staphylococcus intermedius. Journal of Clinical Microbiology. ,vol. 29, pp. 373- 375 ,(1991) , 10.1128/JCM.29.2.373-375.1991
Russell T. Greene, Stefan Schwarz, Small antibiotic resistance plasmids in Staphylococcus intermedius Zentralblatt für Bakteriologie. ,vol. 276, pp. 380- 389 ,(1992) , 10.1016/S0934-8840(11)80545-1
V. HAJEK, Staphylococcus intermedius, a New Species Isolated from Animals International Journal of Systematic and Evolutionary Microbiology. ,vol. 26, pp. 401- 408 ,(1976) , 10.1099/00207713-26-4-401
St. Schwarz, M. Cardoso, S. Grölz-Krug, H. Blobel, Common Antibiotic Resistance Plasmids in Staphylococcus aureus and Staphylococcus epidermidis from Human and Canine Infections Zentralblatt für Bakteriologie. ,vol. 273, pp. 369- 377 ,(1990) , 10.1016/S0934-8840(11)80440-8
H B Drugeon, M E Juvin, J Caillon, A L Courtieu, Assessment of formulas for calculating critical concentration by the agar diffusion method. Antimicrobial Agents and Chemotherapy. ,vol. 31, pp. 870- 875 ,(1987) , 10.1128/AAC.31.6.870