Estimation of Corticotropin-Releasing Activity of Rat Hypothalamus and Neurohypophysis Before and After Stress1

摘要: A method is described for the quantitative measurement of corticotropin- releasing activity crude hypothalamic and neurohypophysial extracts. The involves blood ACTH concentrations 1.25 min after an intracarotid injection extract into female cortisol-blocked rats. corticotropin-releasing posterior lobe pituitary can largely be accounted by its vasopressin content was not measurable acute stress. appears to concentrated in median eminence region shows a marked rapid increase (Endocrinology 75: 514, 1964)