Correlates for completion of 3-dose regimen of HPV vaccine in female members of a managed care organization.

摘要: OBJECTIVE To examine the rate and correlates of completion quadrivalent human papillomavirus vaccine (HPV4) 3-dose regimen because nonadherence to may adversely affect efficacy. PARTICIPANTS AND METHODS Female members Kaiser Permanente Southern California who were 9 26 years old, received first dose HPV4 between October 2006 March 2007, maintained health plan membership 12 months afterward identified followed up for completion. We examined following: (1) demographics/socioeconomic status, (2) primary care physician characteristics, (3) historical service utilization, (4) women's health-related conditions, (5) selected immune-related conditions their association with in 2 age groups: 17 18 years. Multivariable log-binomial regression was used directly estimate relative risk (RR). RESULTS Of 34,193 females initiated HPV4, 41.9% 9- 17-year-old group 47.1% 18- 26-year-old group. Black race (RR, 0.70; 95% confidence interval [CI], 0.64-0.77) lower neighborhood education level associated However, those covered by state-subsidized program Medi-Cal more likely complete 1.14; CI, 1.07-1.22). Historical hospitalizations emergency department visits 0.92; 0.87-0.96; RR, 0.96; 0.94-0.98 per visit, respectively) having a pediatrician also predictors noncompletion. A history sexually transmitted diseases, abnormal Papanicolaou test results, (eg, asthma/infections) not CONCLUSION These findings suggest that factors such as or socioeconomic status should be considered when vaccination programs are being designed evaluated.