摘要: Most individuals diagnosed with a mental illness are not violent, but some mentally ill patients commit violent acts. PubMed database was searched for articles published between 1980 and November 2013 using the combination of key words “schizophrenia” or “bipolar disorder” “aggression” “violence.” In comparison general population, there is approximately twofold increase risk violence in schizophrenia without substance abuse comorbidity ninefold such comorbidity. The bipolar disorder at least as high schizophrenia. occurs during manic phase. Violence among adults may follow two distinct pathways: one associated antisocial conduct another acute psychopathology, particularly anger delusions. Clozapine most effective treatment aggressive behavior Emerging evidence suggests that olanzapine be second treatment. Treatment nonadherence greatly increases behavior, poor insight well hostility nonadherence. Nonpharmacological methods aggression increasingly important. Cognitive behavioral approaches appear to cases where pharmacotherapy alone sufficient.