作者: M. Rossi , M. V. Cubellis , R. Rella , F. Pisani , M. Moracci
DOI: 10.1007/978-3-642-76056-3_7
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摘要: Biotechnological applications of proteins and enzymes are often hampered by their low stability to heat, pH, organic solvents, proteolysis. With the aid protein engineering, however, many attempts being made improve operational current commercial enzymes, and, in a more general sense, establish guidelines for improving thermostability (Mozhaev et al. 1988).