Perioperative Management of Deep Hypothermic Circulatory Arrest

摘要: thermic component significantly decreases brain metabolism and oxygen requirements thus permits a longer period of interrupted blood perfusion to the brain. The cerebral metabolic rate is related exponentially (core body) temperature, with decreasing by about 50% for each 6°C drop in temperature.6 Disadvantages DHCA include increased cardiopulmonary bypass (CPB) time, edema formation, coagulopathy, alteration many organ functions including kidney, brain, vascular smooth muscles, intestinal mucosa, alveolar epithelium, liver, pancreas. 7,8 Based on reports from 8 major cardiac surgery centers United States, Europe, Japan, risk permanent neurologic injury after aortic arch using ranged 3% 12%, renal dysfunction 5% 14%, pulmonary insufficiency 39%, left ventricular