作者: Lee YeongYeh Lee YeongYeh , AA Wirz , JGH Whiting , EV Robertson , D Smith
DOI: 10.1136/GUTJNL-2013-305803
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摘要: Objective There is a high incidence of inflammation and metaplasia at the gastro-oesophageal junction (GOJ) in asymptomatic volunteers. Additionally, majority patients with GOJ adenocarcinomas have no history reflux symptoms. We report effects waist belt increased circumference (WC) on physiology Design 12 subjects normal WC, matched for age gender were examined fasted following meal belts off. A magnet was clipped to squamo-columnar (SCJ). Combined assembly magnet-locator probe, 12-channel pH catheter 36-channel manometer passed. Results The WC each associated proximal displacement SCJ within diaphragmatic hiatus (relative upper border lower oesophageal sphincter (LOS), peak LOS pressure point inversion point, PIP (all p Conclusions Our findings indicate that volunteers, central obesity cause partial herniation short-segment acid reflux. This provides plausible explanation occurrence neoplasia without