In vitro evidence of decompression bubble dynamics and gas exchange on the luminal aspect of blood vessels: Implications for size distribution of venous bubbles.

摘要: We found that lung surfactant leaks into the bloodstream, settling on luminal aspect of blood vessels to create active hydrophobic spots (AHS). Nanobubbles formed by dissolved gas at these AHS are most probably precursors micronuclei and decompression bubbles. Sheep stretched microscope slides, exposed under saline hyperbaric pressure, were photographed following decompression. Photographs an from a pulmonary vein, containing large numbers bubbles, selected in 1-min sequences over period 7 min, starting 18 min after 1,013 kPa. This showed bubble detachment, coalescence expansion, as well competition for between There was greater expansion peripheral than central suggest dynamics bubbles surface vessel may be closest approximation true physiology, such can used assess calibrate models further discuss implications size venous circulation.