Age-associated increases in FKBP51 facilitate tau neurotoxicity

作者: Laura J. Blair

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参考文章(129)
Kazuhide Yahata, Kazuhiro Maeshima, Takefumi Sone, Taichi Ando, Masaru Okabe, Naoko Imamoto, Fumio Imamoto, cHS4 insulator-mediated alleviation of promoter interference during cell-based expression of tandemly associated transgenes. Journal of Molecular Biology. ,vol. 374, pp. 580- 590 ,(2007) , 10.1016/J.JMB.2007.09.054
M. Gossen, H. Bujard, Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 5547- 5551 ,(1992) , 10.1073/PNAS.89.12.5547
Alix de Calignon, Manuela Polydoro, Marc Suárez-Calvet, Christopher William, David H. Adamowicz, Kathy J. Kopeikina, Rose Pitstick, Naruhiko Sahara, Karen H. Ashe, George A. Carlson, Tara L. Spires-Jones, Bradley T. Hyman, Propagation of Tau Pathology in a Model of Early Alzheimer’s Disease Neuron. ,vol. 73, pp. 685- 697 ,(2012) , 10.1016/J.NEURON.2011.11.033
Florence Clavaguera, Tristan Bolmont, R. Anthony Crowther, Dorothee Abramowski, Stephan Frank, Alphonse Probst, Graham Fraser, Anna K. Stalder, Martin Beibel, Matthias Staufenbiel, Mathias Jucker, Michel Goedert, Markus Tolnay, Transmission and spreading of tauopathy in transgenic mouse brain Nature Cell Biology. ,vol. 11, pp. 909- 913 ,(2009) , 10.1038/NCB1901
Alix de Calignon, Leora M. Fox, Rose Pitstick, George A. Carlson, Brian J. Bacskai, Tara L. Spires-Jones, Bradley T. Hyman, Caspase activation precedes and leads to tangles Nature. ,vol. 464, pp. 1201- 1204 ,(2010) , 10.1038/NATURE08890
Tao Zhang, Adel Hamza, Xianhua Cao, Bing Wang, Shuwen Yu, Chang-Guo Zhan, Duxin Sun, A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells Molecular Cancer Therapeutics. ,vol. 7, pp. 162- 170 ,(2008) , 10.1158/1535-7163.MCT-07-0484
Tina R. Hubler, Wesley B. Denny, Donna L. Valentine, Joyce Cheung-Flynn, David F. Smith, Jonathan G. Scammell, The FK506-Binding Immunophilin FKBP51 Is Transcriptionally Regulated by Progestin and Attenuates Progestin Responsiveness Endocrinology. ,vol. 144, pp. 2380- 2387 ,(2003) , 10.1210/EN.2003-0092
Jiacheng Ma, Kevin L. Farmer, Pan Pan, Michael J. Urban, Huiping Zhao, Brian S. J. Blagg, Rick T. Dobrowsky, Heat Shock Protein 70 Is Necessary to Improve Mitochondrial Bioenergetics and Reverse Diabetic Sensory Neuropathy following KU-32 Therapy Journal of Pharmacology and Experimental Therapeutics. ,vol. 348, pp. 281- 292 ,(2014) , 10.1124/JPET.113.210435