Aprotinin: Pharmacological Benefits and Safety Concerns
作者： Andrea Székely , Daniel J. Lex , Béla Merkely
DOI: 10.1007/978-3-319-02186-7_16
关键词:
摘要: In cardiac surgery, perioperative blood transfusion carries considerable risk of complications and increases resource utilization. Antifibrinolytics, particularly aprotinin, have been used effectively to reduce bleeding needs. 2008, the manufacturer withdrew aprotinin from market due discontinued “Blood conservation using antifibrinolytics in a Randomized Trial” (BART) study, which showed an increased mortality associated with use aprotinin.
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sci-hub.st 参考文章(11)
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