摘要: * Abbreviations: Hib — : Haemophilus influenzae b PCV pneumococcal conjugate vaccine Antibiotics pose a great public health irony. Their existence and use have made possible the treatment of previously untreatable infections. But simultaneously, rampant antibiotic overuse has promoted development resistance new untreatable, highly resistant To address this growing threat, The National Action Plan for Combating Antibiotic-Resistant Bacteria established goal to reduce inappropriate outpatient by 50% 2020.1 Antibiotic stewardship, or effort measure improve use, is central component in achieving aims promote facilitate judicious use. In addition problems resistance, also poses other significant threats, including adverse drug events Clostridium difficile infections, consequences that can be mitigated stewardship. Additionally, young children especially infants, who receive more antibiotics per capita than any age group, are particularly vulnerable associated with … Address correspondence Adam L. Hersh, MD, PhD, Division Infectious Diseases, Department Pediatrics, University Utah, 295 Chipeta Way, Salt Lake City, UT 84108. E-mail: adam.hersh{at}hsc.utah.edu