Evaluation of the anti-ulcerogenic activity of a dry extract of Maytenus ilicifolia Martius ex. Reiss produced by a jet spouted bed dryer.

摘要: We undertook the present study to evaluate activity of dried extract Maytenus ilicifolia against stomach ulcers and in increase volume pH gastric juice Wistar rats, as a model viability Jet Spouted Bed Dryer for production dry-extracts medicinal Brazilian plants. The was obtained from drying hydro-alcoholic with aid (40% colloidal SiO2 related solid content concentrated extract, at concentration 15.82% water). conditions employed were: Temperature spouting gas 150 degrees C, feed flow-rate 16.0 g/min, flow rate 1.67 m3/min static bed height 7.0 cm. rats received three different doses (140, 280 420 mg/kg) by intraperitoneal way and, after 60 minutes, were immobilized wire screen placed temperature 4 C two hours (cold-restraint stress). animals sacrificed removed, examined secretion determined. A significant reduction ulceration index, observed well all administered. This is an indication that preparation extracts spouted technique does not alter biological ilicifolia.