Resistance of strongylid nematodes to anthelmintic drugs and driving factors at Czech goat farms

摘要: BACKGROUND Strongylid nematode infections may negatively affect both animal health and welfare, with deleterious consequences for livestock productivity. Many farmers in recent decades have relied on anthelmintics as the sole strategy of control, but intensive use these chemotherapeutics has led to development anthelmintic resistance (AR). Knowledge efficacy factors promoting AR are essential effectively control infections, no information topics goats Czech Republic (CR) is available. This survey aimed determine occurrence at goat farms identify risk AR. A total 24 herds dairy across CR were evaluated using vitro tests detecting AR, a questionnaire was carried out evaluate associated RESULTS Resistance against benzimidazoles confirmed 18 (75%) farms, level high four (22%) affected based egg hatch test. Ivermectin-resistant nematodes detected 13 (54%) larval test; Teladorsagia/Trichostrongylus Haemonchus predominant types resistant larvae. Eight (62%) highly ivermectin. Eleven (46%) report first dual CR. univariate logistic regression analysis indicated that stocking rate farmer inexperience significantly ivermectin benzimidazole resistance, respectively. CONCLUSIONS The results our suggest widespread amongst CR, likely due inappropriate practices pasture management. be an issue expanding dairy-goat production near future unless veterinary practitioners widely adopt strategies prevent