The role of goblet cells in viral pathogenesis.
作者： Stacey Schultz-Cherry , Valerie Cortez
DOI: 10.1111/FEBS.15731
关键词:
摘要: Goblet cells are specialized epithelial that essential to the formation of mucus barriers in airways and intestines. Armed with an arsenal defenses, goblet can rapidly respond infection but must balance this response maintaining homeostasis. Whereas cell defenses against bacterial parasitic infections have been characterized, we just beginning understand their responses viral infections. Here, outline what is known about enteric respiratory viruses target cells, direct bystander effects caused by how interactions barrier alter course infection. Together, these factors play a significant role driving pathogenesis disease outcomes.
sci-hub.st 参考文章(136)
Michael J. Ripple, Dahui You, Srinivasa Honnegowda, Joseph D. Giaimo, Andrew B. Sewell, David M. Becnel, Stephania A. Cormier, Immunomodulation with IL-4Rα Antisense Oligonucleotide Prevents Respiratory Syncytial Virus-Mediated Pulmonary Disease Journal of Immunology. ,vol. 185, pp. 4804- 4811 ,(2010) , 10.4049/JIMMUNOL.1000484
Clark C. Chen, Michael Baylor, Dorsey M. Bass, Murine intestinal mucins inhibit rotavirus infection Gastroenterology. ,vol. 105, pp. 84- 92 ,(1993) , 10.1016/0016-5085(93)90013-3
Malin E.V. Johansson, Hedvig E. Jakobsson, Jessica Holmén-Larsson, André Schütte, Anna Ermund, Ana M. Rodríguez-Piñeiro, Liisa Arike, Catharina Wising, Frida Svensson, Fredrik Bäckhed, Gunnar C. Hansson, Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization. Cell Host & Microbe. ,vol. 18, pp. 582- 592 ,(2015) , 10.1016/J.CHOM.2015.10.007
Dan R. Halm, Susan Troutman Halm, Secretagogue response of goblet cells and columnar cells in human colonic crypts. American Journal of Physiology-cell Physiology. ,vol. 277, ,(1999) , 10.1152/AJPCELL.1999.277.3.C501
Jeremiah R. McDole, Leroy W. Wheeler, Keely G. McDonald, Baomei Wang, Vjollca Konjufca, Kathryn A. Knoop, Rodney D. Newberry, Mark J. Miller, Goblet cells deliver luminal antigen to CD103 + dendritic cells in the small intestine Nature. ,vol. 483, pp. 345- 349 ,(2012) , 10.1038/NATURE10863
Nico Derichs, Byung‐Ju Jin, Yuanlin Song, Walter E. Finkbeiner, A. S. Verkman, Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching The FASEB Journal. ,vol. 25, pp. 2325- 2332 ,(2011) , 10.1096/FJ.10-179549
Svetlana Becker, Tobias A. Oelschlaeger, Andy Wullaert, Manolis Pasparakis, Jan Wehkamp, Eduard F. Stange, Michael Gersemann, Bacteria Regulate Intestinal Epithelial Cell Differentiation Factors Both In Vitro and In Vivo PLoS ONE. ,vol. 8, pp. e55620- ,(2013) , 10.1371/JOURNAL.PONE.0055620
Debby van Riel, Michael A. den Bakker, Lonneke M.E. Leijten, Salin Chutinimitkul, Vincent J. Munster, Emmie de Wit, Guus F. Rimmelzwaan, Ron A.M. Fouchier, Albert D.M.E. Osterhaus, Thijs Kuiken, Seasonal and Pandemic Human Influenza Viruses Attach Better to Human Upper Respiratory Tract Epithelium than Avian Influenza Viruses American Journal of Pathology. ,vol. 176, pp. 1614- 1618 ,(2010) , 10.2353/AJPATH.2010.090949
Thaher Pelaseyed, Joakim H. Bergström, Jenny K. Gustafsson, Anna Ermund, George M. H. Birchenough, André Schütte, Sjoerd van der Post, Frida Svensson, Ana M. Rodríguez-Piñeiro, Elisabeth E. L. Nyström, Catharina Wising, Malin E. V. Johansson, Gunnar C. Hansson, The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system Immunological Reviews. ,vol. 260, pp. 8- 20 ,(2014) , 10.1111/IMR.12182
Malin E. V. Johansson, Fast Renewal of the Distal Colonic Mucus Layers by the Surface Goblet Cells as Measured by In Vivo Labeling of Mucin Glycoproteins PLoS ONE. ,vol. 7, pp. e41009- ,(2012) , 10.1371/JOURNAL.PONE.0041009