Making a Neural Tube: Neural Induction and Neurulation
作者： Raj Ladher , Gary C. Schoenwolf
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摘要: The future central nervous system is derived from an unspecified sheet of ectoderm, with fate being instructed by signals emanating, in the main, a specialized region early embryo, organizer. organizer secretes that have net effect inhibiting BMP pathway, be it extra-cellular antagonism or intracellular modulation ability cell to perceive signals. Other factors also play role neural induction, for example, FGF family molecules, but their exact induction remain unknown. As more players are identified what undoubtedly will signaling network leading molecular mechanism can established.
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