Synthesis and antimicrobial screening of 2-alkyl(aryl)-7-chloro-6-fluoro-4-(trifluoromethyl)-quinolines and their phenylacetylene derivatives, promoted by Sonogashira cross-coupling reaction
作者： Helio G. Bonacorso , Melissa B. Rodrigues , Sarah C. Feitosa , Helena S. Coelho , Sydney H. Alves
DOI: 10.1016/J.JFLUCHEM.2017.11.014
关键词:
摘要: … To a magnetically stirred solution of 3-chloro-4-fluoroaniline (2) (1 mmol; 0.145 g) in ethanol (4 mL), 4-methoxy-1,1,1-trifluorobut-3-en-2-ones (1a–f) or 1-methoxy-2-trifluoroacetyl-3,4-…
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