Maternal Factors Affecting the Vitamin D Content of Human Milk

摘要: The antirachitic activity of human milk has been estimated using a variety techniques during the past several years (1–9). earlier studies were dependent upon rat line biological assay to provide crude estimates total (1–3). Later utilized chemical methods that proved be totally unreliable in estimating vitamin D content (4–6). Only recently actual determined procedures based on high-performance liquid chromatography (HPLC) and/or competitive protein binding (CPBA) (7–13). These have demonstrated: 1) sulfate does not contribute milk; 2) many compounds exist 3) 25-hydroxyvitamin (25-OH-D) contributes vast majority activity; 4) maternal factors such as diet, ultraviolet light exposure and race greatly affect milk. This last aspect, effect status her milk, is relatively new reported great detail. Thus, it purpose this report detailed comprehensive review area nutritional investigation.