Solitary borrelial lymphocytoma in adult patients.

摘要: During the period from 1986 to 2000, 85 adult patients with solitary borrelial lymphocytoma were diagnosed at Department of Infectious Diseases, University Medical Centre Ljubljana, Slovenia. There 36 (42.4%) females and 49 (57.6%) males a median age (15-74) years. Borrelial was located on breast (nipple--areola mammae region) in 68 (80%) patients, ear lobe eight (9.4%), other locations nine (10.6%). A concomitant erythema migrans enabling clinical diagnosis Lyme borreliosis registered or reported 67 (78.8%) patients. Fifteen (17.6%) had no accompanying symptoms, 34 (40%) local constitutional 23 (27.1%) recounted only 13 (15.3%) solely symptoms. Clinical findings indicating early disseminated infection observed first visit 12 (14.1%) patients: six (7.1%) multiple migrans, one meningitis, meningoradiculitis arthritis, radiculoneuritis peripheral facial palsy two arthritis. In addition, acrodermatitis chronica atrophicans. seropositive response antigens found 30 (35.3%) initial examination. 11/46 (23.9%) Borrelia burgdorferi sensu lato confirmed by isolation agent tissue. Eight out (88.9%) typed strains be B. afzelii, (11.1%) bissettii. Patients treated doxycycline, azithromycin, amoxycillin, cefuroxime-axetil, phenoxymethylpenicillin, ceftriaxone. Median time complete disappearance 28 days (range 7-270 days) after institution antibiotic treatment; took longer prolonged duration skin lesion prior treatment. Treatment failure 11 (12.9%) who later re-treated. The outcome assessed end follow-up year favourable.