A new in-bag system to reduce the risk of tissue morcellation: development and experimental evaluation during laparoscopic hysterectomy

摘要: Minimal invasive approaches have proven beneficial for patients undergoing myomectomy and hysterectomy, but necessary tissue morcellation carries the risk of cell dissemination in rare cases inadvertent malignancy. Performing process within a contained bag system may prevent spilling therefore enhance safety laparoscopic procedures. The present study describes development experimental evaluation new vitro vivo pig model supracervical hysterectomies. main results on n = 8 procedures with in-bag compared to controls without indicate reproducible feasibility protective effect bag, which is first published our knowledge that does not require puncturing standard multiport laparoscopy setting. Overall surgery time was significantly prolonged group by 12.86 min (P = 0.0052; 95 % confidence interval 4.64–21.07), peritoneal washings were negative muscle cells all use, positive cytology 5/8 (P = 0.0256). Clinical trials will now be investigate reproducibility these encouraging data human application.