作者: X XIONG , W BAEYENS , H ABOULENEIN , J DELANGHE , T TU
DOI: 10.1016/J.TALANTA.2006.04.038
关键词:
摘要: A tert-butyl carbamoylated quinine-based chiral stationary phase (CSP) for direct enantiomer separation of various natural and unnatural amino acid derivatives was studied. The influence functional groups in the side chains upon enantioseparation is discussed with aim realizing contributions to their overall recognition. effects amines as co-modifiers retention enantioselectivity polar organic solvents systematically investigated. In general, times decreased increasing amine concentrations without a distinct alteration enantioselectivity. All analytes were rapidly resolved on CSP methanol-based mobile containing 87 mM acetic 7 triethylamine.