作者: Margaret Fahnestock , Virginia G. Rimer , Ruth M. Yamawaki , Pepi Ross , Peter D. Edmonds
DOI: 10.1016/0301-5629(89)90162-2
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摘要: Mechanisms of action ultrasound on cell membranes were studied two murine C1300 neuroblastoma lines minimum genetic diversity. Cavitation was established in rotating polystyrene centrifuge tubes by 1 MHz cw ultrasound; exposure time 5 minutes. NS20Y and N2A cells exposed suspension responded similarly 86Rb+ transport Na+-K+-ATPase activity assays, but differently trypan blue dye exclusion lysis assays. This indicates similar overall damage to the membranes, despite use trypsin release N2As only. Primary evidence NS20Ys permeabilization N2As. These results indicate that same conditions can produce different effects differ their membrane properties.